Physicians are concerned about the overuse of acid suppressants and other gastroprotectants in people. Now, veterinarians are scrutinizing the use of these agents in dogs and cats.

The good news is that acid suppressants — like omeprazole — reduce the production of stomach acid that contributes to ulcer formation. However, lowering stomach acidity can interfere with the absorption of other medications. The same is true of stomach-coating agents, like sucralfate.

Changing the acid environment of the stomach has other downsides, too. Gastric acidity protects the digestive tract against certain bacteria, like Salmonella and Campylobacter. So, less acidity may increase the risk of intestinal infections.

Gastroprotectants are beneficial in certain cases. But if they aren’t necessary, the risks may outweigh the benefits.