Cats develop many cancers that are very similar to cancers people experience. Due to the shared environment, many conditions that predispose people to cancer, such as cigarette smoke, pesticides, and pollution, can also affect cats. Because of these similarities, cats, as well as dogs, can be great models for human disease. Dr. Souza will discuss a new clinical trial at UF that will address cats with oral cancer and how they might benefit from potential therapies already available to humans. Cats are also unique in the way they show clinical signs of disease and how they respond to treatment, and Dr. Souza will discuss how veterinarians account for this to ensure improvement in quality of life from the first exam to post-treatment evaluation.