During times of stress, our bodies and brains can react in a variety of ways. Our muscles often tense, we can become irritable and our heart rate increases.
But scientists in a recent study have shown that our brains may counter stress by releasing naturally occurring cannabinoids, also known as endocannabinoids. These cannabinoid molecules activate the same receptors in the brain that are engaged as a response to THC from cannabis plants.
The study revealed that when mice were exposed to stress, the amygdala [uh-mig-duh-luh] — the part of the brain that processes emotions — produced the cannabinoid molecules in response. The endocannabinoids then dampened stress signals coming from the brain’s hippocampus, which is tied to emotion and memory.
The study results bolster the hypothesis that cannabinoid molecules are one of the body’s natural coping mechanisms for stress.
Evidence suggests that impairments to the cannabinoid signaling system in the brain may lead to mood disorders often related to stress. These include anxiety, depression and post-traumatic stress disorder. This could help to inform the treatment and understanding of mood disorders.
The study, conducted by researchers at Northwestern University, helps lay the groundwork for future research. Scientists say the next step is exploring whether boosting endocannabinoids could be used as a therapy for mood disorders. With some clinical trials underway, they say we may know the answer in the not-so-distant future.
The next time you’re feeling anxious, take heart: Your brain is likely hard at work trying to help you out by producing stress-relieving cannabinoids.